Expresión de búsqueda: VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1 
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Descriptor Inglés:   Vascular Endothelial Growth Factor Receptor-1 
Descriptor Español:   Receptor 1 de Factores de Crecimiento Endotelial Vascular 
Descriptor Portugués:   Receptor 1 de Fatores de Crescimento do Endotélio Vascular 
Sinónimos Inglés:   VEGFR-1  
Categoría:   D08.811.913.696.620.682.725.400.950.100
D12.776.543.750.060.750.100
D12.776.543.750.750.400.910.100
Definición Inglés:   A 180-kDa VEGF receptor found primarily in endothelial cells that is essential for vasculogenesis and vascular maintenance. It is also known as Flt-1 (fms-like tyrosine kinase receptor-1). A soluble, alternatively spliced isoform of the receptor may serve as a binding protein that regulates the availability of various ligands for VEGF receptor binding and signal transduction. 
Nota Histórica Inglés:   2003; use VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1 (NM) 1990-2002; for FLK-1 RECEPTOR TYROSINE KINASE use RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR (NM) 1993-2002 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   37358 
Identificador Único:   D040281 

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